(Publications before 2015)

Wang T, Birsoy K, Hughes NW, Krupczak KM, Post Y, Wei JJ, Lander ES, Sabatini DM. Identification and characterization of essential genes in the human genome. Science. 2015 Nov 27;350(6264):1096-101. doi: 10.1126/science.aac7041. Epub 2015 Oct 15. PubMed PMID: 26472758; PubMed Central PMCID: PMC4662922.

**Birsoy K, Wang T, Chen WW, Freinkman E, Abu-Remaileh M, Sabatini DM. An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis. Cell. 2015 Jul 30;162(3):540-51.  doi: 10.1016/j.cell.2015.07.016. PubMed PMID: 26232224; PubMed Central PMCID: PMC4522279.

Kim D, Fiske BP, Birsoy K, Freinkman E, Kami K, Possemato RL, Chudnovsky Y,Pacold ME, Chen WW, Cantor JR, Shelton LM, Gui DY, Kwon M, Ramkissoon SH, LigonKL, Kang SW, Snuderl M, Vander Heiden MG, Sabatini DM. SHMT2 drives glioma cellsurvival in ischaemia but imposes a dependence on glycine clearance. Nature. 2015 Apr 16;520(7547):363-7. doi: 10.1038/nature14363. Epub 2015 Apr 8. PubMed PMID: 25855294; PubMed Central PMCID: PMC4533874.

Lu YH, Dallner OS, Birsoy K, Fayzikhodjaeva G, Friedman JM. Nuclear Factor-Y  is an adipogenic factor that regulates leptin gene expression. Mol Metab. 2015 Feb 13;4(5):392-405. doi: 10.1016/j.molmet.2015.02.002. eCollection 2015 May. PubMed PMID: 25973387; PubMed Central PMCID: PMC4420997.