2016

Garcia-Bermudez J, Birsoy K. Drugging ACAT1 for Cancer Therapy. Mol Cell. 2016 Dec 1;64(5):856-857. doi: 10.1016/j. molcel.2016.11.023. PubMed PMID: 27912096. *corresponding author

**Chen WW, Freinkman E, Wang T, Birsoy K, Sabatini DM. Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism. Cell. 2016 Aug 25;166(5):1324-1337.e11. doi: 10.1016/j.cell.2016.07.040. PubMed PMID:27565352; PubMed Central PMCID: PMC5030821.

Pacold ME, Brimacombe KR, Chan SH, Rohde JM, Lewis CA, Swier LJ, Possemato R, Chen WW, Sullivan LB, Fiske BP, Cho S, Freinkman E, Birsoy K, Abu MR, Shaul YD,Liu CM, Zhou M, Koh MJ, Chung H, Davidson SM, Luengo A, Wang AQ, Xu X, Yasgar A, Liu L, Rai G, Westover KD, Heiden MG, Shen M, Gray NS, Boxer MB, Sabatini DM. A PHGDH inhibitor reveals coordination of serine synthesis andone-carbon unit fate. Nat Chem Biol. 2016 Jul 19;12(8):656. doi:10.1038/nchembio0816-656. PubMed PMID: 27434767.

Chidley C, Trauger SA, Birsoy K, O'Shea EK. The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine. Elife. 2016 Jul 12;5. pii: e14601. doi:

10.7554/eLife.14601. PubMed PMID: 27403889; PubMed Central PMCID: PMC4942256.